Skip to main content
Premium Trial:

Request an Annual Quote

Phase Genomics Wins $200K Grant to Develop Microbiome Discovery Tech

NEW YORK (GenomeWeb) — Phase Genomics said today that it has received a $200,000 grant from the Bill & Melinda Gates Foundation to develop a computational platform for extracting genomic information from microbiome samples.

Seattle-based Phase offers research services and kits based on its Hi-C and proximity-ligation technologies, which enable chromosome-scale genome assembly, metagenomic deconvolution, and the analysis of structural genomic variation and genome architecture.

With the one-year grant, the company said it will develop a platform to identify species and strains of bacteria that cannot be cultured or detected with standard methods. Applications include the discovery of new gut microbes and the ways they colonize mother and child.

"By collaborating with Phase Genomics on the development of metagenomic proximity-ligation technology, we hope to increase our understanding of the microbes that impact human health, with a focus on understudied samples from the developing world," Stanford University researcher and Phase collaborator Justin Sonnenburg said in a statement. "Our goal is to produce a tool that will make the highest resolution microbiome analysis accessible to researchers around the globe."

In mid-2018, Phase was awarded a two-year, $1.5 million grant from the National Institutes of Health to develop an affordable, high-throughput Hi-C kit and computational analysis platform for microbiome research and discovery.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.