Skip to main content
Premium Trial:

Request an Annual Quote

Perkin-Elmer, Hyseq Offer Early Access to Universal DNA Chip

Premium

NORWALK, Conn.--While Perkin-Elmer and Hyseq,of Sunny vale, Calif., continue to streamline the sample analysis process associated with their new HyChip technology, the companies have announced that they will offer pharmaceutical research companies early access to the new universal DNA chip. Hyseq will continue to refine the HyChip sequencing chemistry in addition to the production of the chip component at its facility. Automated reagent delivery instruments and HyChip analyzers are under development at Perkin-Elmer's Applied Biosystems Division. PE Applied Biosystems will manufacture, package, and sell the DNA-target-specific labeled probes.

The companies said the HyChip will provide a significant improvement over current technologies that require specific chips to be manufactured for specific tests. Hyseq's patented Sequencing by Hybridization technology will be broadly available in point-of-use applications, the company said.

The technology utilizes a single complete set of all n-mers probes (currently, 1,024 pentamers) in conjunction with a target-specific cocktail of labeled probes and DNA ligase to identify single nucleotide differences between a reference and a test sample. The use of a universal set of probes allows for arrays to be developed at low density.

Filed under

The Scan

Gone, But Now Reconstructed SARS-CoV-2 Genomes

In a preprint, a researcher describes his recovery of viral sequences that had been removed from a common database.

Rare Heart Inflammation Warning

The Food and Drug Administration is adding a warning about links between a rare inflammatory heart condition and two SARS-CoV-2 vaccines, Reuters reports.

Sandwich Sampling

The New York Times sent tuna sandwiches for PCR analysis.

Nature Papers Describe Gut Viruses, New Format for Storing Quantitative Genomic Data, More

In Nature this week: catalog of DNA viruses of the human gut microbiome, new dense depth data dump format to store quantitative genomic data, and more.