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People in the News: Christine Garnett, Subha Madhavan


Certara has hired Christine Garnett to serve as a principal scientist.

In her role, Garnett will lead efforts to develop cardiac safety modeling tools on the company’s Phoenix software platform and she will also work closely with Pharsight's global consulting services team on predictive modeling engagements that leverage early clinical study data to assess the cardiac proarrhythmic risk of new drug candidates.

Garnett has more than 15 years of experience in clinical pharmacology and cardiovascular safety, including exposure-response modeling for regulatory decisions, population pharmacokinetic analysis, and evaluation of concentration-QTc data for optimal trial design and dose selection.

Prior to joining Certara, she served as team leader in the US Food and Drug Administration’s division of pharmacometrics and as the scientific leader of the FDA's interdisciplinary review team for QT studies. She has also led pharmacometrics teams in multiple therapeutic areas such as oncology, metabolism, and gastroenterology.

Georgetown University Medical Center has tapped Subha Madhavan to serve as the inaugural director of its newly launched Innovation Center for Biomedical Informatics.

Madhavan is the director of clinical research informatics at GU’s Lombardi comprehensive cancer center. Prior to joining the university, she was the associate director of product and program management for life science informatics at the National Cancer Institute’s Center for Biomedical Informatics and Information technology.

She holds a doctorate in molecular biology from the Uniformed Services University for Health Sciences and a master's degree in computer information systems from the University of Maryland.

The Scan

Guidelines for Ancient DNA Work

More than two dozen researchers have developed new ethical guidelines for conducting ancient DNA research, which they present in Nature.

And Cleared

A UK regulator has cleared former UK Prime Minister David Cameron in concerns he should have registered as a consultant-lobbyist for his work with Illumina, according to the Financial Times.

Suit Over Allegations

The Boston Globe reports that David Sabatini, who was placed on leave from MIT after allegations of sexual harassment, is suing his accuser, the Whitehead Institute, and the institute's director.

Nature Papers on Esophageal Cancer, Origin of Modern Horses, Exome Sequencing of UK Biobank Participants

In Nature this week: genetic and environmental influences of esophageal cancer, domestic horse origin traced to Western Eurasian steppes, and more.