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PatternHunter 2.0., ViaCount EasyFit, Treefinder, BIOcrawler, Metabolism PhysioLab, Sun Fire Starter Cluster for Bioinformatics

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Bioinformatics Solutions has released PatternHunter 2.0. The new version of the homology search tool performs gapped alignments, and can also search against arbitrarily large databases without running out of memory, the company said. A demo is at http://www.bioinformaticssolutions.com/products/ph.php.


Guava Technologies has launched ViaCount EasyFit, a cluster analysis algorithm for cell counting and viability measurements for use with its ViaCount Assay technology.


A new version of the Treefinder software for calculating phylogenetic trees is now at http://www.treefinder.de/. Features include fast approximate bootstrapping, a midpoint tree-rooting utility, and a codon position filter.


The National Cancer Institute Center for Bioinformatics has released BIOcrawler, a new client application for the caCORE system that allows users to perform Google-like keyword searches of data in the caCORE systems. It is available at http://ncicb.nci.nih.gov/download/index.jsp.


Entelos said it has upgraded its Metabolism PhysioLab technology to examine progression and regression of type 2 diabetes pathophysiologies; substrate utilization in the liver; and a variety of additional therapies such as insulin secretion enhancers, alpha-glucosidase inhibitors, and DPP-IV inhibitors.


This week, Sun Microsystems will introduce its Sun Fire Starter Cluster for Bioinformatics, an 8 CPU cluster of Sun Fire V60x and V65x servers in a 19-inch rack pre-loaded with Incogen’s VIBE workflow software. The cluster is priced below $22,000, and is available now in North America. Worldwide availability is expected in summer 2004.

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The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.