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Paradigm Genetics, Ingenuity Systems, Millennium Pharmaceuticals, Sun Microsystems, Univ. of Chicago


Paradigm Lays off 50, but Informatics Staff Spared


Paradigm Genetics’ acting CEO John Hamer said last week that despite internal restructuring that resulted in the layoff of 50 employees — 20 percent of its workforce — the company’s informatics staff remains intact.

The layoffs, which primarily affected agricultural research and administrative positions, came as part of a broader restructuring effort within the company, which included the creation of distinct business units for agriculture and human health, a relatively new focus area for the Research Triangle Park, NC-based company.

The informatics team has been split between the business groups to reflect the new project-oriented structure, Hamer said.


Millennium Taps Ingenuity Systems to Create Knowledge Management System


Ingenuity Systems, an Alviso, Calif.-based developer of life science knowledge management solutions, has secured its first customer win with Millennium Pharmaceuticals.

Ingenuity will create a customized knowledge base linking Millennium’s internal research with data from the scientific literature. In turn, Millennium will provide R&D funding to Ingenuity and will make an equity investment in the company.

Ingenuity, founded in October 1998, has developed a proprietary biological ontology and a knowledgebase of over 500,000 findings extracted from the scientific literature and restructured based on the ontology.


U of Chicago Named Sun COE in Bioinformatics


Sun Microsystems has selected the University of Chicago as its latest Center of Excellence in bioinformatics, computational biology and medical informatics.

Sun will install a large computational cluster based on Solaris and Sun’s Grid Engine software. Hardware will include a Sun Fire 6800 enterprise server with 4.6 terabytes of storage housed in Sun StorEdge T3 arrays; a Sun Fire V880 and a Sun Fire 280Rs; a technical compute farm with 52 processors and other servers for high-performance bioinformatics computing; and several dozen Sun Blade 1000 desktops and Sun Ray appliances.

Filed under

The Scan

Shape of Them All

According to BBC News, researchers have developed a protein structure database that includes much of the human proteome.

For Flu and More

The Wall Street Journal reports that several vaccine developers are working on mRNA-based vaccines for influenza.

To Boost Women

China's Ministry of Science and Technology aims to boost the number of female researchers through a new policy, reports the South China Morning Post.

Science Papers Describe Approach to Predict Chemotherapeutic Response, Role of Transcriptional Noise

In Science this week: neural network to predict chemotherapeutic response in cancer patients, and more.