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Oncomine Concepts Map, Star P 2.5, E-WorkBook Suite 7, ExacTag 2.0, UniProt Release 11, BioModels Database

Compendia Bioscience has released Oncomine Concepts Map, an extension of its flagship product, Oncomine Professional. The map combines roughly 7,000 Oncomine cancer gene signatures with 11,000 gene, protein, drug, and pathway signatures culled from the literature and other public sources.
The new technology uses gene sets to compare and link divergent biological concepts.

Interactive Supercomputing has released a new version of its Star-P software designed for life science research.
Star P 2.5 for Life Sciences is an interactive parallel computing platform that allows users to code algorithms and models on their desktops using tools such as Python or Matlab.
According to the company, the software also features a two- to three-fold performance improvement for fast Fourier transform functions on distributed data.

IDBS, which provides data management, analysis and decision support software, has released E-WorkBook Suite 7.
An extensible electronic lab notebook, the workbook is designed for research scientists across many disciplines, with particular relevance for the company’s growing roster of biology clients, IDBS said.
Workbook 7 offers enhanced metadata capture and searching as well as PDF document generation and storage.
The release includes integration capabilities through a web server as well as an application program interface.

PerkinElmer this week upgraded the software for its ExacTag multiplex platform for quantitative protein-expression profiling.
The software, called ExacTag 2.0, is included with the company’s ExacTag Labeling Kits for simultaneous comparisons of two, four, seven, or 10 samples using any tandem mass spectrometer.
The software uses signal intensity measurements from low mass reporter ions as well as protein identification data from packages such as Mascot or Sequest.

The Uniprot Consortium has released UniProt Release 11. The new version includes 4,646,608 UniProtKB entries; 4,628,722 UniRef90 entries; and 1,496,064 UniParc entries. Changes made since the release of version 10 are accessible here.

The European Bioinformatics Institute has released its eighth version of the BioModels Database. The new release adds 34 models, 27 entering the curated branch, for a total of 7,684 reactions.

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The Scan

Study Examines Insights Gained by Adjunct Trio RNA Sequencing in Complex Pediatric Disease Cases

Researchers in AJHG explore the diagnostic utility of adding parent-child RNA-seq to genome sequencing in dozens of families with complex, undiagnosed genetic disease.

Clinical Genomic Lab Survey Looks at Workforce Needs

Investigators use a survey approach in Genetics in Medicine Open to assess technologist applications, retention, and workforce gaps at molecular genetics and clinical cytogenetics labs in the US.

Study Considers Gene Regulatory Features Available by Sequence-Based Modeling

Investigators in Genome Biology set sequence-based models against observational and perturbation assay data, finding distal enhancer models lag behind promoter predictions.

Genetic Testing Approach Explores Origins of Blastocyst Aneuploidy

Investigators in AJHG distinguish between aneuploidy events related to meiotic missegregation in haploid cells and those involving post-zygotic mitotic errors and mosaicism.