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Nucleic Acids Research, Materials Studio 4.1, MDL Assay Explorer 3.1

Nucleic Acids Research has published its annual database issue, which includes papers describing 68 new databases and updates of 106 existing databases. The NAR Molecular Biology Database Collection — a resource with links to the databases described in the issue, previous NAR database issues, and other molecular biology databases — includes 968 databases, 110 more than the previous one. The issue is freely available to subscribers and non-subscribers here.

Accelrys has integrated Materials Studio 4.1 with the CambridgeCrystallographicDataCenter’s Cambridge Structural Database. Users can now initiate a CSD search directly from Materials Studio to retrieve atomic coordinate and other information for more than 400,000 crystal structures.

Elsevier MDL has released MDL Assay Explorer 3.1. The release includes Assay Explorer for Excel, which allows biologists to create, view, and analyze experiments in an Excel spreadsheet while capturing the data in a central repository.

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The Scan

Harvard Team Report One-Time Base Editing Treatment for Motor Neuron Disease in Mice

A base-editing approach restored SMN levels and improved motor function in a mouse model of spinal muscular atrophy, a new Science paper reports.

International Team Examines History of North American Horses

Genetic and other analyses presented in Science find that horses spread to the northern Rockies and Great Plains by the first half of the 17th century.

New Study Examines Genetic Dominance Within UK Biobank

Researchers analyze instances of genetic dominance within UK Biobank data, as they report in Science.

Cell Signaling Pathway Identified as Metastasis Suppressor

A new study in Nature homes in on the STING pathway as a suppressor of metastasis in a mouse model of lung cancer.