NSF, NIH Set Aside $5M Per Year for Research in Mathematical Biology
The National Science Foundation and the National Institute of General Medical Sciences at the National Institutes of Health have launched a joint program to support research in mathematics and statistics related to mathematical biology research.
According to the program solicitation, “Joint DMS/NIGMS Initiative to Support Research in the Area of Mathematical Biology,” NSF intends to provide $2 million per year and NIGMS will provide $3 million per year to support 15 to 20 awards with durations of three to five years.
The program is designed to “support research on mathematical problems related to biological problems in areas supported by NSF/DMS and NIH/NIGMS,” the agencies said in the program solicitation. Successful proposals will identify “innovative mathematics or statistics needed to solve an important biological problem,” and research that applies “standard mathematics or statistics” to solve biological problems is not considered appropriate.
Examples of areas of research that are considered appropriate under the program include evolutionary theory and practice arising from genomic advances; statistical and other approaches to the discovery of genes contributing to complex behavior, and their environmental interactions; explanatory and predictive models of the cellular state; growth, motility, cell division, membrane trafficking, and other cellular behavior; metabolic circuitry and dynamics; population dynamics; signal transduction; development of new algorithms for phylogenetic analysis; design principles and dynamics of pattern formation in development and differentiation; new approaches to the prediction of molecular structure; improved algorithms for structure determination by x-ray crystallography, NMR and electron microscopy; and new approaches to understanding system-wide effects of pharmacological agents and anesthetics, and their genetic and environmental modifiers.
Proposals are due by Dec. 15.
Institut Pasteur Korea to Use IDBS ActivityBase
IDBS said this week that Institut Pasteur Korea has implemented its ActivityBase data-management software suite for its high-throughput and high-content screening operations.
Institut Pasteur Korea, based in Seoul, South Korea, will use ActivityBase to integrate chemistry information and screening results from microscopy-based screens.
Financial terms of the agreement were not disclosed.
Geneva Bioinformatics, Insilicos Bundle Platforms, Pen Reseller Deals
Geneva Bioinformatics will bundle its Phenyx mass spec data-analysis software with Insilicos' Proteomics Pipeline as part of a reseller agreement, the companies said this week.
Terms of the deal call for Insilicos to be the exclusive global reseller of a bundled Phenyx/IPP offer, while GeneBio will be the exclusive European reseller.
In addition, GeneBio and Insilicos have acquired the right to non-exclusively sell each other's products in Europe and North America, respectively.
WashingtonStateUniversity Extends License to GeneGo's MetaCore
Washington State University Tri-Cities has extended its license to GeneGo’s MetaCore pathway analysis platform, the company said this week.
John Miller, associate professor at Washington State University Tri-Cities and emeritus staff member at Pacific Northwest National Labs, said in a statement that his research group has been using MetaCore under the Department of Energy's Low Dose Radiation Research Program.
He said that his team has been using the system to interpret proteomic data from irradiated cells and to identify pathways responsible for cytokine release following radiation exposure
Financial terms and other details of the agreement were not provided.
U of Louisville to Host Cattle SNP Data for DNA-Based Traceback Development
The University of Louisville's Center for Genetics and Molecular Medicine said this week that it has released cattle SNP data that will be used to develop DNA-based traceback markers for beef and dairy cattle in the US and Canada.
The data, available here, will be used to develop genetic tests for tracing animals “from the farm to the dinner plate,” CGeMM said. The center is partnering with the US Department of Agriculture’s Agricultural Research Service and Cogenics, a division of Clinical Data, on the project.
Ted Kalbfleisch, director of bioinformatics operations at CGeMM, said in a statement that the SNP data is the “first step” in a broader data-management system under development at the center.
“Today we are providing access to a very specialized SNP marker set for traceback, parentage, and identification,” Kalbfleisch said, “but ultimately the project will create a web-services based system with value-added functions and the information that scientists need to write analysis tools for their particular bioinformatics systems."
The DNA-based traceback marker system is a collaboration between scientists at the US Meat Animal Research Center in Clay Center, Neb.; the Bovine Functional Genomics Laboratory in Beltsville, Md.; the University of Alberta's Beef Genomics Laboratory in Edmonton, Canada; and Cogenics, based in Morrisville, NC.
UK's BBSRC to Dole Out $66M for Systems Biology Research
The UK’s Biotechnology and Biological Sciences Research Council announced two initiatives worth over £35 million ($66 million) to encourage systems biology research.
BBSRC and the Engineering and Physical Sciences Research Council committed £30 million to the Systems Approaches to Biological Research Initiative. The initiative will fund projects in 2007 to increase systems biology research being conducted in universities and institutes.
BBSRC and EPSRC invested £43.6 million in six university-based systems biology centers in 2005. Researchers from those centers are invited to participate in the second initiative, worth £5 million. The Exploiting Systems Biology LINK Initiative will allow them to work with industrial collaborators who will contribute at least 50 percent of full cost of each project.
The centers are at the universities of Edinburgh, Manchester, Newcastle, Nottingham, Oxford, and Imperial College, London.