CAMBRIDGE, Mass.--One Cell Systems here was awarded a $400,000 Phase II Small Business Innovation Research grant from the National Science Foundation to develop a high-throughput method for screening transfected cells based on their level of protein secretion. The technology relies on the combination of microencapsulation using gel microdrops, a novel secreted protein capture format, and fluorescence-activated cell sorting. Live, intact, high secretor or rare cells are recovered for subsequent cloning in a streamlined one-day process.
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