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NIH to Award $1.4M Per Year to Develop Integrative Data Analysis Tools for LINCS Program


The National Human Genome Research Institute and the National Heart, Lung, and Blood Institute plan to grant up to $1.4 million per year over the next two years to fund the development of computational tools for the Library of Integrated Network-based Cellular Signatures, or LINCS, program, according to a recent announcement from the National Institutes of Health.

According to the grant summary, the NIH is looking for “grant applications that would develop innovative computational tools and approaches for the integrative analysis of multiple types of data generated within the LINCS program.“

The program will fund four awards in fiscal year 2011 for up to two years at $250,000 in research costs per year, NIH said.

Letters of intent must be received by Jan. 22, 2011, and applications should be received by Feb. 22 with Sept. 1, 2011, as the earliest anticipated start date.

Now in its early stages, the LINCS program was set up to “develop a ‘library’ of molecular signatures, based on gene expression and other cellular changes that describe the response that different types of cells elicit when exposed to various perturbing agents, including siRNAs and small bioactive molecules.”

According to the NIH, the first phase of the project will focus on large-scale production of perturbation-induced molecular and cellular signatures, computational tool development and integrative data analyses, and integration of existing datasets into the LINCS database among other activities.

More information about the award program can be found here.

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