Next-Gen Phred: Vendors, Academics Address Quality Scoring Methods for the $1,000 Genome | GenomeWeb

Phred, the base-calling algorithm developed by Phil Green and colleagues at the University of Washington in the late 90s, is the de facto standard for assessing the quality of Sanger-based sequence data. But as next-generation sequencing technologies enter the market, researchers are finding that similar methods to assign confidence to their results could use some validation of their own.

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