CLEVELAND--Bioinformatics firm Netgenics got its start here two-and-a-half years ago with $1.5 million in venture capital. "Then," said CEO Manuel Glynias, "we made what was probably a stupid decision. We hired enough people that the $1.5 million wouldn't last through the whole year."

Two financing rounds and a few deals later, however, Netgenics is thriving and Glynias is confident in the market for his company's cornerstone product, Synergy, a Corba- and Java-based software framework for drug-discovery computing.

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