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National Library of Medicine, NIH, GenoLogics, University of Glasgow, CXR Biosciences, Rosetta, University of Leuven, 454, Sequenom, VBI, Clinical Data, GraphLogic, Serono

NLM Awards $75M for Biomedical Informatics Training Programs
The National Library of Medicine this week said it has awarded a series of grants totaling more than $75 million to fund training in biomedical informatics.
The 18 grants awarded by the NLM, a branch of the National Institutes of Health, will fund five-year programs around the country in a number of areas, including healthcare and clinical informatics, bioinformatics and computational biology, translational informatics, public health informatics, and imaging and signal processing.
The training will target physicians, biologists, computer scientists, and engineers, the NLM said.
Training centers funded by the NLM include Johns Hopkins University, Rice University, Harvard University, the University of Washington, and 16 other education institutions.
Recipients of the funding are responsible for selecting trainees and implementing program specifics, the NLM said.
Further information about the training programs and a complete list of grant recipients is available here

NIH Commits $6M to Develop Analytical Methods for Gene-Environment Interaction Studies
The National Institutes of Health has set aside $6 million in funding over the next three years to support the development of methods for identifying gene-environment interactions in genome-wide association studies. 
According to a request for applications NIH issued this week titled, “Methods of Analysis of Gene-Environment Interactions in Complex Diseases: The Genes and Environment Initiative,” NIH expects to award five grants at up to $400,000 in total costs per year per award.
NIH has earmarked $2 million in fiscal year 2007 for the program, which falls under the broader Genes and Environment Initiative, a four-year, NIH-wide program proposed in the President’s FY 2007 budget and currently awaiting Congressional approval.
According to the RFA, NIH is seeking applicants who will “develop and test innovative, informative, and cost-effective methods and analytical strategies for identifying gene-environment interactions in genome-wide association studies, sequencing studies, linkage analyses, or candidate gene approaches with broad applicability in complex diseases.”
Examples of approaches that would be relevant under the RFA include, but are not limited to:
  • Analytical methods that model combinations of SNPs and environmental exposures to detect nonlinear interactions;
  • Analytical methods that incorporate environmental covariates in genotype-to-phenotype mapping relationships;
  • Algorithms and strategies to evaluate non-genetic factors on phenotypes of complex diseases and test associations between SNPs, or haplotypes and phenotypes;
  • Novel approaches to analyze findings from pharmacogenomic studies.
Letters of intent are due Dec. 29 and applications are due Jan. 29, 2007.

Scottish Genomics Lab to Use GenoLogics' Geneus, Proteus Software
A genomics facility in Scotland will use GenoLogics’ Geneus and Proteus software for its genomics and proteomics research, GenoLogics said this week.
The products will be used at the University of Glasgow’s Sir Henry Wellcome Functional Genomics Facility and the RASOR Interdisciplinary Research Collaboration, an initiative involving several British universities.
Financial terms of the deal were not disclosed. 

CXR Licenses Rosetta’s Resolver System
CXR Biosciences has licensed Rosetta Biosoftware’s Resolver system, the companies said this week.
CXR, a Dundee, Scotland-based drug developer, said it will use the software to determine the toxicological profiles of early-stage compounds.
Financial terms of the deal were not released.

BelgianProteomicsCenter Chooses GenoLogics’ Proteus Software
GenoLogics Life Sciences Software announced this week that the ProMeta Interfaculty Center for Proteomics and Metabolomics at the University of Leuven in Belgium will use its Proteus software package.
In a statement, the company said that Proteus will increase automation of instruments and data integration with downstream search engine processes, resulting in a decrease in turnaround time.

454, Sequenom, VBI, Clinical Data License GraphLogic Application-Development Technology
GraphLogic said this week that 454 Life Sciences, Sequenom, the Virginia Bioinformatics Institute, and Clinical Data have recently licensed its application-development technology.
GraphLogic said that its codeless application builder “provides the benefits of a custom laboratory operations solution without the prohibitive cost and lengthy development time that plague custom systems created with traditional software technology.”

Serono Expands License for IDBS BioBook
IDBS said this week that Serono has expanded its use of IDBS’ electronic study management tool BioBook.
Serono first licensed BioBook in December 2005. Following the initial rollout, Serono has now decided to more than double its number of BioBook users, IDBS said.
Financial terms of the expanded license agreement were not provided.

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