Skip to main content
Premium Trial:

Request an Annual Quote

mpiBlast, DNAStar s Lasergene 6, John Innes Center and Affymetrix, OpenEye Scientific Software s Ogham and LexiChem, Infotrieve s Infotrieve/ELN 2.4, and Nucleic Acids Research


An updated version of mpiBlast, a parallelized version of NCBI Blast, is expected to be released next week, Aaron Darling of the University of Wisconsin-Madison, the lead developer for the software, told BioInform at ISMB last week. The new release, version 1.4, offers a 350-fold speed-up over NCBI Blast on a 128-CPU cluster, Darling said. The software is available at

DNAStar has released an updated version of its Lasergene 6 sequence analysis software to support Mac OS X Tiger (10.4). Lasergene 6 Mac users who have upgraded to OS 10.4 can download and install the Lasergene Tiger update at

The John Innes Center in Norwich, UK, has released an Affymetrix expression module for its Genome Laboratory Information Management System (GenomeLIMS). The system is free for academic researchers at GeneChip customers can use the system to submit and track samples through the expression workflow from initial sample QC using the BioAnalyzer to final data QC from the Affymetrix report files. Sample information is automatically parsed into the GCOS expression format.

OpenEye Scientific Software has released Ogham and LexiChem, programs for 2D rendering, compound naming, and the generation of structures from names. Ogham renders 2D drawings from 3D structures or connectivity information. LexiChem converts chemical names into chemical structures and vice versa. Both products are available either as standalone applications or as C++ toolkits for in-house or third-party software-development purposes.

Infotrieve has released Infotrieve/ELN 2.4, an electronic laboratory notebook enterprise software package. The product is built on the GenSys/ELN, which Infotrieve acquired in its purchase of GenSys software in December 2004.

Nucleic Acids Research has published its annual web server issue, which includes 159 papers describing 166 web-based computational tools for analyzing DNA, RNA, and protein sequences and structures. The issue is freely available to subscribers and non-subscribers at A complete listing of the 2005 NAR servers is available at


Filed under

The Scan

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.

US Survey Data Suggests Ancestry Testing Leads Way in Awareness, Use of Genetic Testing Awareness

Although roughly three-quarters of surveyed individuals in a Genetics in Medicine study reported awareness of genetic testing, use of such tests was lower and varied with income, ancestry, and disease history.

Coral Genome Leads to Alternative Amino Acid Pathway Found in Other Non-Model Animals

An alternative cysteine biosynthesis pathway unearthed in the Acropora loripes genome subsequently turned up in sequences from non-mammalian, -nematode, or -arthropod animals, researchers report in Science Advances.

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.