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MolQuest 1.0, TL120, IPLab 4.0, IntEnz 21, BIRCH A1.98, Steve Levine, Carl Turza

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Softberry has released MolQuest 1.0, a desktop sequence analysis package that brings together around 100 Softberry programs, including the company's FGENESH family of eukaryotic genefinding programs; its TSSG, TSSP, and NSITE regulatory region finders; and several genome comparison tools. A trial version of the software is available at http://www.molquest.com.


Nonlinear Dynamics has released an updated version of TL120 (formerly Phoretix 1D), a software package for analyzing 1D gel data. TL120 includes an extended set of image-editing tools along with enhanced gel visualization and improved usability options, the company said. It is available for both PC and Mac users.


BD Biosciences' Bioimaging Systems unit has released IPLab 4.0. The new version of the image acquisition, processing, and analysis software package includes a new multidimensional acquisition feature to simplify complex live cell time-lapse experiments, as well as an advanced analysis toolbar for processing and analyzing a single image or multiple images quickly.


The European Bioinformatics Institute has released IntEnz (Integrated Enzyme Database) 21 at http://www.ebi.ac.uk/intenz/. IntEnz 21 has 4,738 Enzyme Commission numbers, of which 93 are proposed enzymes.


The Department of Plant Science at the University of Manitoba has released BIRCH (Biological Research) A1.98 at http://home.cc.umanitoba.ca/~psgendb. BIRCH includes freely available programs and databases for molecular biology.

People in the News

Steve Levine has joined Dassault Systems as senior director of corporate development for the company's Simulia physics simulation software division, which it picked up in its October 2005 acquisition of Abaqus. Levine was formerly senior director of corporate development at Accelrys. He has also held management positions at Molecular Simulations, Biosym Technologies, and Engelhard.


Sigma-Aldrich has named Carl Turza as chief information officer, effective May 1. Turza will lead the company's information technology and Internet functions. Turza previously held senior IT management positions at W.W. Grainger, AlliedSignal Aerospace, and several other organizations.

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The Scan

Genetic Tests Lead to Potential Prognostic Variants in Dutch Children With Dilated Cardiomyopathy

Researchers in Circulation: Genomic and Precision Medicine found that the presence of pathogenic or likely pathogenic variants was linked to increased risk of death and poorer outcomes in children with pediatric dilated cardiomyopathy.

Fragile X Syndrome Mutations Found With Comprehensive Testing Method

Researchers in Clinical Chemistry found fragile X syndrome expansions and other FMR1 mutations with ties to the intellectual disability condition using a long-range PCR and long-read sequencing approach.

Team Presents Strategy for Speedy Species Detection in Metagenomic Sequence Data

A computational approach presented in PLOS Computational Biology produced fewer false-positive species identifications in simulated and authentic metagenomic sequences.

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.