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ModView, GenBank, Genomic XML Viewer, Genesis, GeneCards, UDB


Version 0.879 of ModView from Rockefeller University is now available at modview.

New features of ModView, a program to visualize and analyze multiple biomolecular structures and/or sequence alignments, include extended coloring and viewing options and multiple structure representation.

GenBank release 124.0 is available via ftp from the National Center for Biotechnology Information at

Release 124.0 contains 12,973,707,065 base pairs and 12,243,766 entries, compared with 12,418,544,023 base pairs and 11,545,572 entries in the April 123.0 release. The 124.0 flat files require approximately 46.4 GB for the sequence files only. The ASN.1 version requires approximately 42.4 GB.

LabBook of McLean, Va., has released an enhanced version of its Genomic XML Viewer, a desktop application for converting and viewing documents in BSML (bioinformatic sequence markup language). The new version gives users access to the EMBL, Ensembl, Swiss-Prot, and GenBank databases.

Separately, the European Bioinformatics Institute announced that it has adopted the BSML format for EMBL database sequence output.

The Genomic XML Viewer runs under Windows and is available for free at

Gene Logic, based in Gaithersburg, Md., formally launched its enterprise-wide expression data analysis system, Genesis, at the BIO 2001 conference last week in San Diego.

Genesis can be used as a standalone product or can be fully integrated with Gene Logic’s GeneExpress database suite. It contains a proprietary connector component for gene expression data acquisition and validation, as well as migration of the data into an Oracle 8i-hosted data warehouse. Genesis offers a gene expression analysis engine and user interface to perform data exploration and analysis.

The company expects the software to be available for installation at customer sites in late third-quarter or fourth-quarter 2001.

GeneCards 2.21 and UDB 2.21a are now available from the Weizmann Institute of Science at

New features include 22,420 genes and 44 gene clusters, improved graphics developed by DoubleTwist, an improved algorithm for linking cards to the University of California Santa Cruz Golden Path, and information on C. elegans homologs from the State University of New York at Stony Brook C. elegans-H. sapiens Alignment Database.


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The Scan

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.

Researchers Retrace Key Mutations in Reassorted H1N1 Swine Flu Virus With Avian-Like Features

Mutations in the acidic polymerase-coding gene boost the pathogenicity and transmissibility of Eurasian avian-like H1N1 swine influenza viruses, a PNAS paper finds.

Genome Sequences Reveal Evolutionary History of South America's Canids

An analysis in PNAS of South American canid species' genomes offers a look at their evolutionary history, as well as their relationships and adaptations.

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.