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Michael Savage, Wendell Jones, Brian Zambrowicz

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Blackstone Computing of Worcester, Mass., has appointed Michael Savage as chairman of the board. Savage was president of Molecular Simulations from 1991 to 1999 and then served as director and vice president of Pharmacopeia, which acquired MSI (now Accelrys).

Research Triangle Park, NC-based microarray genetics testing firm Expression Analysis has hired Wendell Jones as senior research statistician. Jones, who previously worked as a senior software reliability engineer for IBM and was the manager of research and technology at Nortel Networks, will support EA’s bioinformatics and analysis division.

Brian Zambrowicz, formerly senior vice president of genomics at Lexicon Genetics, has been promoted to executive vice president of research of the Woodlands, Texas-based company. Zambrowicz’ responsibilities will include forming new drug discovery partnerships while continuing to manage Lexicon’s existing alliances and oversee basic genomic discovery research.

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The Scan

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.

DNA Storage Method Taps Into Gene Editing Technology

With a dual-plasmid system informed by gene editing, researchers re-wrote DNA sequences in E. coli to store Charles Dickens prose over hundreds of generations, as they recount in Science Advances.

Researchers Model Microbiome Dynamics in Effort to Understand Chronic Human Conditions

Investigators demonstrate in PLOS Computational Biology a computational method for following microbiome dynamics in the absence of longitudinally collected samples.

New Study Highlights Role of Genetics in ADHD

Researchers report in Nature Genetics on differences in genetic architecture between ADHD affecting children versus ADHD that persists into adulthood or is diagnosed in adults.