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MetaMiner Cystic Fibrosis, Nexus Copy Number Professional Version 3 Human Oral Microbiome Database, ProCKSI, TopMatch-web, RasMol

GeneGo has released MetaMiner Cystic Fibrosis, a software and database platform focused on integrating and analyzing cystic fibrosis data. The company developed the platform with support from Cystic Fibrosis Foundation Therapeutics, a non-profit affiliate of the Cystic Fibrosis Foundation.
The system includes a database of experimental information on the disease and more than 30 CF-specific pathway maps and networks.

BioDiscovery has released Nexus Copy Number Professional Version 3, a data-integration tool that allows researchers to process thousands of arrays and their clinical annotations. The software is compatible with the Agilent, Affymetrix, Illumina, Roche Nimblegen, and Empire Genomics array platforms.
The new release also enables the integration of external gene expression and miRNA results with copy number analysis data so that researchers can overlay this information on chromosomal aberration regions.

The Forsyth Institute and King's College London have released the Human Oral Microbiome Database, or HOMD, here. The free online database includes information on oral microorganisms, including biological entries for each species and a catalog of genes.
The database categorizes each microbe by its 16S rRNA sequence. For those organisms whose DNA has been sequenced, HOMD provides online tools to view and analyze their genes and proteins.

The University of Nottingham has released the Protein Structure Comparison, Knowledge, Similarity, and Information, or ProCKSI, server.
ProCKSI computes structural similarities using a range of similarity measures in order to produce a similarity consensus. The resource also provides links to external resources with information about protein structures, and provides tools for visualizing, analyzing, and comparing results.

The University of Salzburg has released TopMatch-web, a public web service for the alignment and superposition of protein structures and the visualization of structural similarities.

RasMol is available here.
New features in the molecular graphics program include support for maps, support for Bulgarian, Chinese, English, Italian, Japanese, Russian, and Spanish messages, and support for the wwPDB remediated PDB format. 

Filed under

The Scan

Guidelines for Ancient DNA Work

More than two dozen researchers have developed new ethical guidelines for conducting ancient DNA research, which they present in Nature.

And Cleared

A UK regulator has cleared former UK Prime Minister David Cameron in concerns he should have registered as a consultant-lobbyist for his work with Illumina, according to the Financial Times.

Suit Over Allegations

The Boston Globe reports that David Sabatini, who was placed on leave from MIT after allegations of sexual harassment, is suing his accuser, the Whitehead Institute, and the institute's director.

Nature Papers on Esophageal Cancer, Origin of Modern Horses, Exome Sequencing of UK Biobank Participants

In Nature this week: genetic and environmental influences of esophageal cancer, domestic horse origin traced to Western Eurasian steppes, and more.