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May's Bioinformatics Papers of Note

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Fernández JM, Gómez-López G, et al.
RUbioSeq: a suite of parallelized pipelines to automate exome variation and bisulfite-seq analyses.
Bioinformatics. 2013 May 24. [Epub ahead of print]


Kuster B, Lemeer S, et al.
MScDB: A Mass Spectrometry-centric Protein Sequence Database for Proteomics.
J Proteome Res. 2013 May 14. [Epub ahead of print]


Guerrero RF, Kirkpatrick M, et al.
A sequential coalescent algorithm for chromosomal inversions.
Heredity (Edinb). 2013 May 1. [Epub ahead of print]


Antonov AV, Barlev NA, et al.
PPISURV: a novel bioinformatics tool for uncovering the hidden role of specific genes in cancer survival outcome.
Oncogene 2013 May 20. [Epub ahead of print]


Afrasiabi C, Dineen D, et al.
The PhyloFacts FAT-CAT web server: ortholog identification and function prediction using fast approximate tree classification.
Nucleic Acids Res. 2013 May 18. [Epub ahead of print]


Deng HW, Duan J, et al.
CNV-TV: A robust method to discover copy number variation from short sequencing reads.
BMC Bioinformatics. 2013 May 2. [Epub ahead of print]


Birol I, Fejes AP, et al.
Identifying cancer mutation targets across thousands of samples: MuteProc, a high throughput mutation analysis pipeline.
BMC Bioinformatics. 2013 May 28. [Epub ahead of print]


Alfaro ME, Balhoff JP, et al.
Phylotastic! Making tree-of-life knowledge accessible, reusable and convenient.
BMC Bioinformatics. 2013 May 13. [Epub ahead of print]


Bacall F, Balcazar Vargas MP, et al.
The Taverna workflow suite: designing and executing workflows of Web Services on the desktop, web or in the cloud.
Nucleic Acids Res. 2013 May 2. [Epub ahead of print]


Alteyrac L, Bouchereau B, et al.
A universal open-source Electronic Laboratory Notebook.
Bioinformatics 2013 May 2. [Epub ahead of print]


Alcantara LC, Assel M, et al.
RegaDB: community-driven data management and analysis for infectious diseases.
Bioinformatics 2013 Jun 1;29(11):1477-1480. Epub 2013 May 2.


Cardoso J, Pereira R, et al.
TNA4OptFlux - a software tool for the analysis of strain optimization strategies.
BMC Res Notes. 2013 May 3;6:175. doi: 10.1186/1756-0500-6-175.


Azad MA, Baylay AJ, et al.
The Comprehensive Antibiotic Resistance Database.
Antimicrob Agents Chemother. 2013 May 6. [Epub ahead of print]


Dubé MP, Legault MA, et al.
pyGenClean: Efficient tool for genetic data clean up before association testing.
Bioinformatics. 2013 May 6. [Epub ahead of print]


Gao N, Tang J, Yang N.
Ancestral genome inference using a genetic algorithm approach.
PLoS One. 2013 May 2


Itoh T, Nakato R, Shirahige K.
DROMPA: easy-to-handle peak calling and visualization software for the computational analysis and validation of ChIP-seq data.
Genes Cells 2013 May 15. [Epub ahead of print]


Ballesteros-Villagrana E, Fu C, et al.
DrugMap Central (DMC), an on-line query and visualization tool to facilitate drug repositioning studies.
Bioinformatics. 2013 May 15. [Epub ahead of print]


Chen T, Jiang R, Zeng F.
PyroHMMsnp: an SNP caller for Ion Torrent and 454 sequencing data.
Nucleic Acids Res. 2013 May 21. [Epub ahead of print]


Bear KA, Nguyen AD, et al.
Clinical Genomic Database.
Proc Natl Acad Sci U S A. 2013 May 21. [Epub ahead of print]


Canzar S, Salzberg SL, et al.
GAGE-B: An Evaluation of Genome Assemblers for Bacterial Organisms.
Bioinformatics 2013 May 10. [Epub ahead of print]


Chang Y, Jiang Y, et al.
HGPGD: The Human Gene Population Genetic Difference Database.
PLoS One. 2013 May 22


Berriman M, Hunt M, et al.
REAPR: a universal tool for genome assembly evaluation.
Genome Biol. 2013 May 27. [Epub ahead of print]


Filed under

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.