Mark Boguski cut his teeth at NCBI at the height of the genome sequencing era before moving on to lead R&D at Rosetta Inpharmatics just as the field of microarray analysis was taking off; in other words, his career has mirrored major shifts in the field of bioinformatics itself. And, judging from Boguski’s latest appointment as director of the newly launched Allen Institute for Brain Science, it looks like the discipline may be poised for another shakeup.

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Robert Redfield is floated as the next director of the US Centers for Disease Control and Prevention, the Washington Post reports.

The New York Times writes that the National Institutes of Health's All of Us Research Program is "ambitious" and that some are concerned it might be overly so.

Representative Lamar Smith's criticism of the National Science Foundation has "changed the nature of the conversation," according to ScienceInsider.

In PLOS this week: non-coding RNA function in yeast, transcriptomic profiles of malaria parasites, and more.