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MAG Announces Commercial Release of Bioinformatics Software


PALO ALTO, Calif.--Molecular Application Group, a bioinformatics software company here, has commercially released GeneMine, a major update of the company's flagship Look product line. According to the manufacturer, the software offers comprehensive data retrieval, integration, and visualization capabilities. It can access public, licensed, and proprietary data sources, as well as collect and display such information as homology clusters, EST tissue expression clusters, homology fingerprints, active sites, functional motifs, posttranslational modifications, and metabolic pathway associations; and sequence polymorphic regions.

GeneMine combines new bioinformatics datamining capabilities with a set of efficient, reliable protein modeling methodologies originally developed in the Look product line, according to Molecular Applications, which called GeneMine "the first in a series of bioinformatics data mining products" that it will develop.

"GeneMine is a paradigm for molecular biology programs in the information age," claimed Timothy Springer, professor of pathology at Harvard University and an early user of the software package. "It enables one to go rapidly from discovery of a new gene to exploration of protein families, prediction of motifs, analysis of structure, and identification of function." Myra Williams, Molecular Applications' president and CEO, added, "Scientists urgently need more effective tools to help them extract meaningful information and derive insight from sequence data. GeneMine addresses this need. It filters, clusters, and graphically arranges the overwhelming volume of information returned from a typical search result, presenting data in a simplified format that allows the user to sift easily through it."

"A major benefit of this system is that it provides multiple independent predictions of structure and function, enabling powerful cross-validation and error detection within search results," noted Chris Lee, a Molecular Applic ations cofounder and vice-president of research. "Bioinformatics analysis systems traditionally follow a paradigm where the user must know all the available tools, how to use them, when to use them, and how to interpret the results. GeneMine was created to entirely automate this process."

Molecular Applications said it will offer GeneMine to academic scientists at a substantial discount.

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