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Locus Pharmaceuticals, Rosetta Biosoftware, Aureus Pharma, BioWisdom

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Locus to Use Computational Drug-Design Platform in Collaboration with Amgen

Locus Pharmaceuticals said this week that it has signed a research agreement with Amgen, under which it will use computational methods to design small-molecule compounds with activity against a target identified by Amgen.

Financial and other terms of the agreement were not disclosed.

"Given our past molecular design experience across 10 classes of protein targets, we are confident that we will identify novel chemical classes of inhibitors for Amgen," said Jeffrey Wiseman, vice president of technology and informatics at Locus.

The company said that it has so far used its proprietary technology in six external collaborations.


Rosetta Biosoftware Uses Borland's ALM for Resolver Development

Borland Software said this week that Rosetta Biosoftware is using its Application Lifecycle Management product line as part of its ongoing development of the Rosetta Resolver analysis platform.

Borland said that Rosetta is using its CaliberRM, StarTeam, and Together lifecycle management products, as well as its consulting services, "to streamline and automate the processes of requirements management, software change and configuration management as well as visual modeling and architectural design."


Siena Biotech Licenses Aureus Pharma's ADME and hERG Databases

Aureus Pharma said last week that Siena Biotech has licensed its AurScope ADME/Drug-Drug Interaction and hERG databases.

Financial terms of the agreement were not disclosed.

The databases "complement our in-house knowledge-based drug design platform," Graeme Robertson, vice president of therapeutic research, said in a statement.


Pfizer to Use BioWisdom's Sofia KnowledgeScan

Pfizer has licensed BioWisdom's Sofia KnowledgeScan platform, BioWisdom said this week.

Sofia KnowledgeScan is a service based on the company's Sofia Intelligence Platform, and provides "contextually relevant information to support critical healthcare-related decision-making," BioWisdom said in a statement.

Financial terms of the agreement were not provided.

Filed under

The Scan

Shape of Them All

According to BBC News, researchers have developed a protein structure database that includes much of the human proteome.

For Flu and More

The Wall Street Journal reports that several vaccine developers are working on mRNA-based vaccines for influenza.

To Boost Women

China's Ministry of Science and Technology aims to boost the number of female researchers through a new policy, reports the South China Morning Post.

Science Papers Describe Approach to Predict Chemotherapeutic Response, Role of Transcriptional Noise

In Science this week: neural network to predict chemotherapeutic response in cancer patients, and more.