Skip to main content
Premium Trial:

Request an Annual Quote

Lexicon Puts Genomics Database on Web, Inks Deals for Knockout Mice

Premium

THE WOODLANDS, Texas--Lexicon Genetics has launched a subscription internet program, allowing commercial and academic or nonprofit institutions to access OmniBank, its proprietary genomics library and database. Using Lexicon's website, http://www.lexgen.com, subscribers can reach 50,000 mouse clones, a collection of knockout mouse embryonic stem cells, and gene sequence information, which can provide predictive information on the action of potential therapeutic drug candidates and the validity of their targets.

Lexicon also announced that it has signed functional genomics agreements with several academic institutions for engineering custom knockout mice, including: Johns Hopkins University; Pennsylvania State University; University of Southern California; University of Rochester; Indiana University School of Medicine; and the Max Planck Society. Under these agreements, the institutions will specify their genes of interest and Lexicon will generate knockout mice. Financial terms of the agreements were not disclosed.

Filed under

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.