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Lasergene v7.2, NCI Terminology Browser, Progeniq Pte, AlleleID

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DNASTAR has released Lasergene v7.2, with expanded assembly and visualization capabilities for traditional and next-generation sequencing. The desktop software allows users to assemble bacterial-size genomes using the 454 Life Sciences pyrosequencing technique and to generate flowgrams diagrams on the same software used for smaller assemblies. 
 
Lasergene is a suite of tools for molecular biologists and geneticists and is used primarily in the assembly and analysis of DNA and protein sequences. The software is compatible with Windows XP and Vista systems and Mac OS 10.3 or higher.
 

 
The Zebrafish Anatomical Ontology is now being served as a standalone vocabulary by the National Cancer Institute’s Enterprise Vocabulary Service. The ontology is freely available via the NCI Terminology Browser and programmatically via the caCORE servers.
 
The zebrafish ontology is a controlled vocabulary of the anatomy and development of the zebrafish (Danio rerio).
 
A display name property has been created, which in the case of anatomical entities contains the zebrafish preferred term suffixed by the developmental start and end stages indicated by the source.
 

 
Progeniq Pte, which offers reconfigurable computing applications, has launched the BioBoost Accelerated Suite for Bioinformatics, which enables up to a 50-fold speedup versus a single 3.5 GHz CPU processor, the company said.
 
BioBoost provides hardware-accelerated processing for NCBI Blast, Smith-Waterman, HMMer, and ClustalW.
 

 
Premier Biosoft released this week version 5 of AlleleID, which helps design microarrays and real-time PCR diagnostic assays. The product, designed for pathogen detection or bacterial identification, now enables the design of probes for multiplex ligation-dependent probe amplification.
 
AlleleID is a desktop tool designed to address pathogen detection, bacterial identification, or taxa/species discrimination using microarrays and TaqMan, TqMan MGB, SYBR Green, and molecular beacon qPCR assays
 
Multiplex ligation-dependent probe amplification is a method to establish the copy number of up to 45 nucleic acid sequences in a single reaction.

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The Scan

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In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies of 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.