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Lasergene, HIV-1 Human Protein Interaction Database, Cancer Chromosomes, PyMOL, Dynamite


DNAStar has released Lasergene v. 5.53 for Macintosh OS X and Lasergene v. 5.08 for Windows and Macintosh classic. Current customers with a valid support contract can log in and download the upgrades at Software changes include an “important fix” related to the Blast search results window that previously resulted in an error message “due to recent changes at NCBI,” the company said. In addition, the new releases include updated transcription factor data supplied by the Institute for Transcriptional Informatics.

The National Center for Biotechnology Information has released the HIV-1 Human Protein Interaction Database at The database includes known interactions of HIV-1 proteins with proteins from human hosts, offering a summary of these interactions with links to PubMed, sequence data, and genes.

NCBI has also released the Cancer Chromosomes database through the Entrez system ( The database contains cytogenetic, clinical, and reference information via the merger of the NCI Mitelman Database of Chromosome Aberrations in Cancer, the NCI Recurrent Aberrations in Cancer Database, and the NCI/NCBI SKY/M-FISH & CGH Database.

Version 1.4 of nuccyl, a PyMOL module that displays nucleic acids and nucleic acid-protein complexes in ribbon and cylinder representations, is available from the Mount Sinai School of Medicine at nuccyl.html.

Dynamite, a web-based program that predicts protein motion using PDB files, is available from the University of Oxford at


Filed under

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.