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Knome to Include HGMD Data in Personal Genomics Offerings

NEW YORK (GenomeWeb News) – Personal genomics outfit Knome said today that it is incorporating data from the Human Gene Mutation Database into its genome-interpretation services.

Knome is incorporating the data through an agreement with German bioinformatics firm Biobase, which is distributing the HGMD data.

Under the agreement, Knome, based in Cambridge, Mass., will include HGMD in its KnomeXplorer genome browser software and its genome interpretation update service.

The data will be continuously updated with the latest findings and distributed to Knome’s clients, giving them direct access to the most up-to-date information on a real-time basis, the company said.

Financial terms of the agreement between Knome and Biobase were not disclosed.

HGMD contains information on more than 93,000 mutations and disease-related polymorphisms in more than 3,500 genes. Typically used by large research institutions and pharmaceutical companies, this is the first time the HGMD data is being made available as part of a consumer offering, Knome and Biobase said.

"Combined with their sequencing capabilities and interpretation services, the addition of our rare mutation database will enable Knome to provide even deeper insight into each client's genetic profile and deliver greater customer value," Michael Tysiak, CEO of Biobase, said in a statement.

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