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Johns Hopkins Taps Knome to Analyze Data for 1K Genome Asthma Study

NEW YORK (GenomeWeb News) – The Johns Hopkins University School of Medicine will use Knome's software and informatics services to analyze data from 1,000 genomes for an asthma study, Knome said today.

The Hopkins researchers will use Knome's software, including the company's KnomeVariants and KnomePathways tools, to identify candidate variants, genes, and gene networks.

As GenomeWeb Daily News reported last month, Hopkins won a $9.5 million grant from the National Heart, Lung, and Blood Institute to sequence the genomes of 1,000 people of African descent. It is partnering with 15 academic centers in the US, the Caribbean, South America, and Western Africa.

The researchers will analyze the genomes of 500 asthmatics and 500 non-asthmatics in order to find genetic explanations for why as many as 20 percent of African Americas have asthma.

Knome said the Johns Hopkins team will use its software to annotate genomes, and to turn the raw sequence information into datasets for use in comparative interpretation.

Financial terms of the agreement were not released.

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