Computational systems biology is giving oncology research a boost at Johnson & Johnson Pharmaceutical Research and Development, where scientists are using technology from Gene Network Sciences, Ariadne Genomics, and GeneGo to elucidate the mechanism of action of potential therapeutics and point the way toward biomarkers related to drug efficacy and response.

Timothy Perera, a principal scientist in the oncology research early development group at J&J PRD Europe, presented early results of this work at the annual Cancer Progress conference in New York on March 8.

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The New York Times and ProPublica say that many physicians fail to disclose their financial ties when publishing in medical journals.

The Wall Street Journal reports Human Longevity's valuation has dropped by 80 percent.

Science reports that the US National Cancer Institute is cutting its operating budget by 5 percent.

In PLOS this week: similar variants seen in bullbogs, people with Robinow syndrome; ApoE genotypes in African-American, Puerto Rican populations; and more.