Skip to main content
Premium Trial:

Request an Annual Quote

Japan Tobacco Is First Customer for Gene Logic's Database


COLUMBIA, Md.--Gene Logic here has announced that it will collaborate with Japan Tobacco to uncover drug targets and leads in kidney disease. Gene Logic will utilize its proprietary Accelerated Drug Discovery platform in the effort. Japan Tobacco will also be the first subscriber to Gene Logic's Gene Express Normal database of quantitative gene expression profiles in a variety of normal tissues of human, rat, and mouse origin. The deal also gives Japan Tobacco the option of accessing Gene Logic's Flow-thru Gene Chip technology for high-throughput screening.

Terms of the deal allow Japan Tobacco to expand the collaboration to other disease areas at any time during the first two years. The company will gain worldwide rights to all small-molecule drugs and therapeutic antibodies and proteins developed under the collaboration. Gene Logic will receive royalties on the sales of any such products, and retains the rights to gene therapy, antisense, and diagnostic products. The agreement also provides that Gene Logic will receive a minimum of $3 million a year from its partner over the predicted five-year life of the collaboration.

Filed under

The Scan

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.

Rett Syndrome Mouse Model Study Points to RNA Editing Possibilities

Investigators targeted MECP2 in mutant mouse models of Rett syndrome, showing in PNAS that they could restore its expression and dial down symptoms.

Investigators Find Shared, Distinct Genetic Contributors to Childhood Hodgkin Lymphoma

An association study in JAMA Network Open uncovers risk variants within and beyond the human leukocyte antigen locus.

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.