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Jackson Lab Wins $25M NIH Grant to Continue Mouse Genome Database

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The National Institutes of Health has awarded a $25 million five-year grant to the Jackson Laboratory to support its Mouse Genome Database, a free repository of information about the laboratory mouse.

The Jackson Lab said it will use the $24.6 million grant from the National Human Genome Research Institute to compile genome-scale data sets for mouse and human. The lab was also awarded a $500,000 supplement to support the Knockout Mouse Project 2 initiative.

As part of the work on MGD, researchers will work on cross-referencing mice genetic information with physiological data and standardizing the vocabulary for diseases, genes, and physical characteristics.

The funds will also be used to pay salaries for the lab’s three dozen researchers, to develop new online tools that help users query the MGD, and to maintain a dedicated support team that will provide technical assistance and training for users.

Jackson Lab’s Janan Eppig said in a statement that MGD’s developers are “actively [soliciting] community input, data submissions, and collaborations” for the database.

Besides MGD, the Jackson lab generates and maintains several open-source databases that are known collectively as Mouse Genome Informatics and support research efforts in cancer, diabetes, osteoporosis, Alzheimer’s disease, and other areas.

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