In an effort to bridge the gap between target discovery and target validation, a research team at Johnson & Johnson Pharmaceutical R&D has merged bioinformatics with high-throughput screening to create a new research strategy they’ve dubbed “functional informatics.” Led by Sergey Ilyin, bioinformatics group leader, the Spring House, Pa.-based R&D group found that integrating several technologies that are traditionally isolated in “research silos” was the best approach to functionally characterizing target molecules.

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