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IP Update: Omicia, Microsoft among Recent Bioinformatics Patent Winners


US Patent 8,417,462. System and method for identifying complex patterns of amino acids. Inventors: Samuel Bogoch, Elenore Bogoch, Samuel Winston Bogoch, Anne Elenore Borsanyi. Assignee: Not Listed

This patent describes a method and system for querying protein databases to identify complex patterns in amino acid sequences.

US Patent 8,417,459. Methods of selection, reporting and analysis of genetic markers using broad-based genetic profiling applications. Inventor: Martin Reese. Assignee: Omicia

This patent describes a method determining an individual’s probability of exhibiting a particular phenotype, providing relevant genetic information to the individual, evaluating the probability of transferring phenotypic attributes in families, and determining the “genomic ethnicity” of an individual.

US Patent 8,412,463. Methods of associating an unknown biological specimen with a family. Inventors: John Douglas Birdwell, Tse-Wei Wang, Dale Stansberry, Ranajit Chakraborty. Assignee: University of Tennessee Research Foundation

This patent describes computational and statistical methods for predicting the familial origins of unknown biological specimens.

US Patent 8,412,462. Methods and systems for processing genomic data. Inventors: Lawrence Ganeshalingham, Patrick Nikita Allen. Assignee: Annai Systems

This patent describes a computational method for processing genomic and other biopolymeric information.

US Patent 8,412,460. Methods and systems for characterizing a cellular constituent using response profiles. Inventors: Roland Stoughton, Timothy Hughes. Assignee: Microsoft

Describes computational methods for characterizing genes and gene products. According to the abstract, the patent is for methods of “assigning or determining the biological function of uncharacterized genes and gene products by using ‘response profiles.’”

US Patent 8,401,802. Halotype estimating apparatus and program. Inventor: Mamoru Kato. Assignee: Riken

Describes a method of estimating a haplotype from genotype data.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.