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IP Update: Microsoft, MathWorks, among Recent Bioinformatics Patent Winners


US Patent 8,521,441. Method and computer product for reducing flurophore-specific bias. Inventors: Roland Stoughton, Hongyue Dai. Assignee: Microsoft

Describes a computer-based method for using data from repeated experiments to "generate a confidence value for each data point, increase sensitivity, and eliminate systematic experimental bias."

US Patent 8,521,438. Computer-implemented cellular modeling parallel pathways. Inventors: Patrick Edson, Ricardo Paxson. Assignee: The MathWorks

This patent is for a computerized method of generating cellular models.

US Patent 8,515,680. Analysis of transcriptomic data using similarity based modeling. Inventors: Robert Pipke, Jack Mott. Assignee: Venture Gain

This patent describes a model-based approach for analyzing genomic, proteomic, and transcriptomic data for use in diagnostics, prognostics and biomarker discovery.

US Patent 8,494,783. Method and apparatus for storing and processing molecular information. Inventor: Hikaru Samukawa. Assignee: International Business Machines

This patent describes a method and apparatus for storing and processing molecular structures.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.