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IP Update: Microsoft, IBM, and Affymetrix among Recent Bioinformatics Patent Winners

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US Patent 8,396,671. Cluster modeling, and learning cluster specific parameters of an adaptive double threading model. Inventors: Nebojsa Jojic, David Heckerman, Manuel Jesus Reyes Gomez. Assignee: Microsoft

This patent describes cluster models that can be used to predict protein and ligand binding.


US Patent 8,392,355. Computer software for visualizing genotyping data. Inventors: Giulia Kennedy, Yaron Turpaz, Chun Zhang. Assignee: Affymetrix

This patent describes a computer-based method of visualizing recombination events in genotype data.


US Patent 8,386,190. System and method for identifying networks of ternary relationships in complex data systems. Inventor: Ker-Chau Li.
Assignee: The Regents of the University of California

This patent is for a system and method of "identifying high order associations between variables in complex systems that is particularly useful where there is no correlation or weak correlation between variables due to the influence of a third variable, a ternary relationship." According to the abstract, the method could be used to analyze gene expression data.


US Patent 8,386,189. Protein Structure Analysis. Inventors: Prasanna Athma, Ajay Royyuru, Benjamin David Silverman, Ruhong Zhou. Assignee: International Business Machines

Describes a method for protein structure analysis that uses a scoring function.


US Patent 8,380,442. Secondary structure defining database and methods for determining identity and geographic origin of an unknown bioagent thereby. Inventors: David Ecker, Richard Griffey, Rangarajan Sampath, Steven Hofstadler, John McNeil, Stanley Crooke. Assignee: Ibis Bioscience

This patent describes methods of interrogating bioagent databases to compare the molecular masses of known and unknown bioagents in order to determine the identities and/or origins of unknown agents.


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The Scan

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A genomic analysis in Nature Microbiology explores how SARS-CoV-2 spread into, across, and from Brazil.

New Study Highlights Utility of Mutation Testing in Anaplastic Thyroid Cancer

Genetic mutations in BRAF and RAS are associated with patient outcomes in anaplastic thyroid carcinoma, a new JCO Precision Oncology study reports.

Study Points to Increased Risk of Dangerous Blood Clots in COVID-19 Patients

An analysis in JAMA Internal Medicine finds that even mild COVID-19 increases risk of venous thromboembolism.

Y Chromosome Study Reveals Details on Timing of Human Settlement in Americas

A Y chromosome-based analysis suggests South America may have first been settled more than 18,000 years ago, according to a new PLOS One study.