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IP Update: Microsoft, IBM, and Affymetrix among Recent Bioinformatics Patent Winners

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US Patent 8,396,671. Cluster modeling, and learning cluster specific parameters of an adaptive double threading model. Inventors: Nebojsa Jojic, David Heckerman, Manuel Jesus Reyes Gomez. Assignee: Microsoft

This patent describes cluster models that can be used to predict protein and ligand binding.


US Patent 8,392,355. Computer software for visualizing genotyping data. Inventors: Giulia Kennedy, Yaron Turpaz, Chun Zhang. Assignee: Affymetrix

This patent describes a computer-based method of visualizing recombination events in genotype data.


US Patent 8,386,190. System and method for identifying networks of ternary relationships in complex data systems. Inventor: Ker-Chau Li.
Assignee: The Regents of the University of California

This patent is for a system and method of "identifying high order associations between variables in complex systems that is particularly useful where there is no correlation or weak correlation between variables due to the influence of a third variable, a ternary relationship." According to the abstract, the method could be used to analyze gene expression data.


US Patent 8,386,189. Protein Structure Analysis. Inventors: Prasanna Athma, Ajay Royyuru, Benjamin David Silverman, Ruhong Zhou. Assignee: International Business Machines

Describes a method for protein structure analysis that uses a scoring function.


US Patent 8,380,442. Secondary structure defining database and methods for determining identity and geographic origin of an unknown bioagent thereby. Inventors: David Ecker, Richard Griffey, Rangarajan Sampath, Steven Hofstadler, John McNeil, Stanley Crooke. Assignee: Ibis Bioscience

This patent describes methods of interrogating bioagent databases to compare the molecular masses of known and unknown bioagents in order to determine the identities and/or origins of unknown agents.


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The Scan

Driving Malaria-Carrying Mosquitoes Down

Researchers from the UK and Italy have tested a gene drive for mosquitoes to limit the spread of malaria, NPR reports.

Office Space to Lab Space

The New York Times writes that some empty office spaces are transforming into lab spaces.

Prion Pause to Investigate

Science reports that a moratorium on prion research has been imposed at French public research institutions.

Genome Research Papers on Gut Microbe Antibiotic Response, Single-Cell RNA-Seq Clues to Metabolism, More

In Genome Research this week: gut microbial response to antibiotic treatment, approach to gauge metabolic features from single-cell RNA sequencing, and more.