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IP Update: Metabolon, IBM, Agilent Among Recent Bioinformatics Patent Winners

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US Patent 8,131,473. Data analysis methods for locating entities of interest within large, multivariable datasets. Inventors: Marie Coffin, Keith Allen, Brian Bullard, Alan Higgins. Assignee: Metabolon

Describes a mathematical approach for identifying and further analyzing subsets of biological molecular data, such as genes or proteins, that are associated with interesting trends in the data that could also serve as biomarkers.


US Patent 8,131,472. Methods for hierarchical organization of data associated with medical events in databases. Inventors: Tony Chow, Robert Friedlander, Anwer Khan, James Kraemer. Assignee: International Business Machines

Describes a method of organizing medical data that involves creating a database in which medical and research events are stored and linked with their associated data "hierarchically," providing researchers with access to data on large numbers of patients that participated in particular medical procedures as well as enabling them to investigate potential relationships.


US Patent 8,131,471. Methods and system for simultaneous visualization and manipulation of multiple data types. Inventor: Robert Kincaid. Assignee: Agilent

Describes software and methods for visualizing and manipulating datasets from microarrays and other biological data in order to facilitate identification, trends, correlations, and other relationships.


US Patent 8,126,655. Information processing system using information on base sequence. Inventors: Takamasa Katoh; Takeo Morimoto Assignee: Hitachi

Describes an information processing system that uses differences between nucleotide sequences to provide useful semantic data for individual organisms.


US Patent 8,122,073. Computational systems for biomedical data. Inventors: Edward Jung, Royce Levien, Robert Lord, Lowell Wood Jr. Assignee: The Invention Science Fund I

Describes a system for identifying agents that are associated with particular treatment targets.


US Patent 8,121,794. Systems and methods for automated analysis of cells and tissues. Inventors: David Rimm, Robert Camp. Assignee: Yale University

Describes a computerized method for analyzing cell samples to identify morphology and to localize and quantitate biomarkers.


US Patent 8,121,793. Method and device for comparative display of biological data . Inventor: Guenther Mohr. Assignee: Eppendorf

Describes a computer system for visualizing data from nucleic acids, proteins, and other biopolymers.


US Patent 8,121,793. Method and device for comparative display of biological data . Inventor: Guenther Mohr. Assignee: Eppendorf

Describes a computer system for visualizing data from nucleic acids, proteins, and other biopolymers.


The Scan

WHO Seeks Booster Pause

According to CNN, the World Health Organization is calling for a moratorium on administering SARS-CoV-2 vaccine boosters until more of the world has received initial doses.

For Those Long Legs

With its genome sequence and subsequent RNAi analyses, researchers have examined the genes that give long legs to daddy longlegs, New Scientist says.

September Plans

The New York Times reports that the US Food and Drug Administration is aiming for early September for full approval of the Pfizer-BioNTech SARS-CoV-2 vaccine.

Nucleic Acids Research Papers on Targeting DNA Damage Response, TSMiner, VarSAn

In Nucleic Acids Research this week: genetic changes affecting DNA damage response inhibitor response, "time-series miner" approach, and more.