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IP Update: Life Tech, Penn State, Selventa Among Recent US Patent Winners


US Patent 8,090,543. Computer algorithm for automatic allele determination from fluorometer genotyping device. Inventor: Stephen Glanowski, Jeremy Heil, Emily Winn-Deen, Ivy McMullen. Assignee: Applied Biosystems (Life Technologies)

Describes a method for "allelic classification" of DNA samples by cluster-based analysis of emission spectra observed from fluorophore-labeled nucleotide probes

US Patent 8,086,414. Method and system for modeling cellular metabolism. Inventor: Costas Maranas, Anthony Burgard. Assignee: The Penn State Research Foundation

Describes a method for in silico modeling of cellular metabolism. The method improves on flux balance analysis models because it incorporates several constraints including qualitative kinetic information, qualitative regulatory information, and DNA microarray data. The approach also includes computational procedures for solving metabolic problems.

US Patent 8,086,410. Methods of detecting DNA variation in sequence data. Inventor: Changsheng Liu, Fei Gao.

Describes a mathematical method using trace data from sample sequences to detect DNA variation.

US Patent 8,082,109. Computer-aided discovery of biomarker profiles in complex biological systems. Inventor: William Ladd, Keith Elliston, Joseph Loureiro. Assignee: Selventa

Describes a computational approach for identifying candidate biomarkers in body fluids and tissue samples.

The Scan

Booster Push

New data shows a decline in SARS-CoV-2 vaccine efficacy over time, which the New York Times says Pfizer is using to argue its case for a booster, even as the lower efficacy remains high.

With Help from Mr. Fluffington, PurrhD

Cats could make good study animals for genetic research, the University of Missouri's Leslie Lyons tells the Atlantic.

Man Charged With Threatening to Harm Fauci, Collins

The Hill reports that Thomas Patrick Connally, Jr., was charged with making threats against federal officials.

Nature Papers Present Approach to Find Natural Products, Method to ID Cancer Driver Mutations, More

In Nature this week: combination of cryogenic electron microscopy with genome mining helps uncover natural products, driver mutations in cancer, and more.