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IP Update: IBM, Trigeminal Solutions, Hitachi among Recent Bioinformatics Patent Winners


Title: Method for reconstructing evolutionary data

US Patent Number: 8,645,074

Assignee: International Business Machines

Inventor: Laxmi Parida

Title: Technique for identifying association variables

US Patent Number: 8,639,446

Assignee: Trigeminal Solutions

Inventor: Steven Stupp

Title: Information processing system using nucleotide sequence-related information

US Patent Number: 8,639,451

Assignee: Hitachi

Inventors: Takamasa Katoh, Takeo Morimoto

Title: Identification of related residues in biomolecular sequences by multiple sequence alignment and phylogenetic analysis

US Patent Number: 8,639,445

Assignee: Microsoft

Inventor: Stuart Ozer

Title: Methods for identifying drug targets based on genomic sequence data

US Patent Number: 8,635,031

Assignee: The Regents of the University of California

Inventor: Bernhard Palsson

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.