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IP Update: Hitachi, 23andMe among Recent Bioinformatics Patent Winners


US Patent 8,433,522. Information processing system using nucleotide sequence-related information. Inventors: Takamasa Kato, Takeo Morimoto. Assignee: Hitachi

This patent is for an information processing system that provides useful semantic information about individual organisms by utilizing differences between genomic sequences in the individuals.

US Patent 8,429,105. Concurrent two-phase completion genetic algorithm multi-processor instance system. Inventor: David Jacobson. Assignee: Not listed

US Patent 8,429,104. Concurrent two-phase completion genetic algorithm multi-processor instance system. Inventor: David Jacobson. Assignee: Not listed

These patents describe systems and methods that implement a genetic algorithm used for processing population data.

US Patent 8,428,886. Genotype calling. Inventors: Alexander Wong, Oleksiy Khomenko, Serge Saxonov, Brian Naughton, Lawrence Hon. Assignee: 23andMe

This patent describes a system for determining the genetic sequence at specific sites in the genome. According to the abstract, it uses measurements associated with the sequences along with contextual information to “compute an improved determination of the genetic sequence at the particular site on the individual's genome.”

US Patent 8,428,882. Method of processing and/or genome mapping of ditag sequences. Inventors: Kuo Ping Chiu, Yijun Ruan, Chia Lin Wei. Assignee: Agency for Science, Technology, and Research

This patent describes a method of processing and mapping ditag nucleotide sequences to genomes.

US Patent 8,423,339. Visual analysis of a protein folding process. Inventors: Laxmi Parida, Ruhong Zhou. Assignee: International Business Machines

This patent describes a system and computerized method of analyzing protein folding. Specifically, it “relates to an incremental pattern discovery method (and system) for analyzing protein folding trajectory data from simulation experiments.”

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.