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Inpharmatica, Schering, Shimadzu,Eidogen-Sertanty, KAI, Genedata, Nonlinear, Ariadne, Infocom, NLM


Inpharmatica Licenses Biopendium and Chematica to Schering

As BioInform reported in September [BioInform 09-29-05], Inpharmatica said last week that it has licensed its Biopendium and Chamatica technologies to Schering as part of a druggability assessment collaboration.

Inpharmatica said that Schering intends to use the technologies to support its protein-prioritization efforts.

The financial terms of the agreement were not disclosed.

Shimadzu to Distribute Phenomenome Discoveries' Metabolomics Software

Phenomenome Discoveries, a Canadian company that provides software tools for metabolomics analysis, said this week that Tokyo-based Shimadzu will become the global distributor for its Phenomenome Profiler software.

Under the agreement, Shimadzu will co-market and distribute PDI's software together with its mass spectrometry product lines for GC/MS and LC/MS.

Financial details were not disclosed.

Eidogen-Sertanty to Use Informatics Platform in Collaboration with KAI

Eidogen-Sertanty said last week that it has entered into an informatics-based collaboration with drug-discovery firm KAI Pharmaceuticals.

Under the terms of the collaboration, which will focus on the development of protein kinase C modulators, Eidogen-Sertanty will use its Target Informatics Platform and its EVE comparative visualization software to perform structural characterization and comparative binding site analysis for PKC regulatory domains.

KAI is developing modulators of PKCs for a variety of human diseases, and has a lead product in clinical development for acute cardiovascular diseases. The collaboration is expected to improve the pharmacophore-based design of modulators of PKC activity, Eidogen-Sertanty said.

Genedata, Nonlinear to Integrate, Co-Market Progenesis and Expressionist

Nonlinear Dynamics and Genedata said last week that they have signed a co-marketing agreement that will create a "more integrated workflow" between Nonlinear's Progenesis 2D gel analysis software and Genedata's Expressionist software.

The companies said that the combined platform will add statistical processing to Progenesis 2D gel image analysis data provide "additional result validation preceding the final [mass spectrometry] identification and sample classification stages of the gel-based workflow."

Ariadne to Add Infocom's Auto Net Finder to PathwayStudio

Ariadne Genomics said last week that it will integrate Infocom's Auto Net Finder software with its PathwayStudio Central client-server pathway analysis platform.

Auto Net Finder uses a combination of network-analysis tools to predict biological networks and estimate "inter-cluster relationships," Infocom said.

With the addition of Auto Net Finder, PathwayStudio Central users will be able to infer regulatory networks from gene expression data and validate them through comparison with Ariadne's ResNet database of functional relationships compiled from literature, Ariadne said.

Auto Net Finder was developed through two-year collaboration between Infocom and Katsuhisa Horimoto at the University of Tokyo's Human Genome Center.

The software will be available as a module for PathwayStudio for an additional fee.

NLM to Publish RFA for Training in Biomedical Informatics

The National Library of Medicine last week issued a notice of intent to publish a request for applications for research training in biomedical informatics.

According to the notice (available at, the RFA will issue in early January, with letters of intent due on Jan. 31 and applications due on March 17.

NLM said it currently supports 18 institutional sites for biomedical informatics training, and that it welcomes renewal applications from those sites as well as new applications from sites that are not currently funded.

Training funded under the RFA will "emphasize the preparation of individuals capable of carrying out independent research in biomedical informatics," which NLM defines as "the intersection of basic informational and computing sciences with a wide range of application domains in biomedicine."

"Funding decisions will be made by September or October 2006 to enable funded sites to begin recruiting trainees for the 2007-2008 academic year," NLM said in the notice.

Grants will be awarded July 1, 2007, for the five-year project period. NLM did not provide any information on total funding that will be made available.

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