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Ingenuity, Geospiza Merge Data-Visualization and Pathway-Analysis Tools for NGS Research


Ingenuity and Geospiza will integrate their Ingenuity Pathway Analysis and GeneSifter software products to create a research workflow for next-generation sequence data analysis and visualization, Ingenuity said this week.

Ingenuity's Chief Scientific Officer and Chief Technology Officer Doug Basset said the partnership aims to help joint customers answer research questions by "providing a streamlined way for researchers to move from a list of genes, isoforms, or variants all the way to identifying drug targets, validating biomarkers, generating hypotheses, and understanding drug mechanism of action."

The partners hope that the combined tools will speed up drug discovery and –omics research by enabling researchers to "visualize their data in the context of known biological processes, functions, diseases, pathways and relationships," said Geospiza Chief Technology Officer Todd Smith.

Ingenuity recently merged IPA with California-based TransMed Systems' XB Bio-Integration Suite — a data analytics and management tool that lets users capture, analyze, visualize, and share their genomic data as well as access multiple genomic data sources, create patient cohorts, and generate hypotheses

The combined platform is expected to enable users to collect and analyze pre-clinical and clinical data in the context of signaling and metabolic pathways, networks, and cellular processes that are available in IPA (BI 10/22/2010).

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.