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InforSense, Johns Hopkins, Genomatix, Gene Logic, Inpharmatica, Ingenuity, and more


InforSense, Elsevier MDL Extend Integration Alliance

InforSense and Elsevier MDL said last week that they have expanded a collaboration that began when Elsevier MDL joined InforSense's Open Workflow Partner Network in March [BioInform 03-14-05].

Under the expanded agreement, InforSense has joined the MDL Isentris Alliance. The companies said they will integrate the MDL Isentris n-tier informatics platform with the InforSense KDE workflow platform, and will "explore further joint development initiatives."

As a member of the InforSense OWPN, Elsevier MDL has already integrated several chemistry applications, including MDL Direct data cartridges and MDL ISIS/Draw, with InforSense KDE and InforSense Oracle Edition.

Johns Hopkins Opens Institute for Computational Medicine …

Johns Hopkins University said last week that it had launched the Institute for Computational Medicine, a new center that will use "powerful information management and computing technologies to produce a better understanding of the origins of human disease."

Raimond Winslow, a professor of biomedical engineering at Johns Hopkins, has been tapped as director of the institute and Aravinda Chakravarti, director of the school's Institute of Genetic Medicine, is co-director. About 20 faculty members are currently affiliated with the institute, and six more faculty members will be added over the next several years.

The ICM is currently operating in existing university space, but a permanent home is planned in the Computational Sciences and Engineering Building, which is now under construction. The building is expected to open in the spring of 2007, and the ICM has reserved up to 11,000 square feet of space.

Johns Hopkins said in a statement that bioinformatics will be one of the institute's "research thrusts," along with molecular-scale biological systems modeling and computational anatomy.

The institute has received around $8 million in startup funding over the next five years from National Institutes of Health, the D. W. Reynolds Foundation, and the Falk Medical Trust.

… and Offers Online Bioinformatics MS

Johns Hopkins also said last week that it has launched an online Master of Science in Bioinformatics.

First classes will start in spring 2006 and applications will be available after Oct. 21. Qualified applicants are expected to have bachelors or advanced degrees in the biological sciences or engineering.

NCI Renews, Expands License to Genomatix Tools

Genomatix Software said last week that the National Cancer Institute has renewed its license agreement for the company's software and databases.

Under the renewed license, NIH intramural researchers nationwide will have full access to the Genomatix suite of tools, as well as ChipInspector, a new single-probe-analysis package that Genomatix expects to release later this year.

Gene Logic, Biogen Idec Barter Rights to Custom Microarray, Database

Gene Logic said last week that it has signed a co-licensing agreement with Biogen Idec under which it will provide genomic services using Biogen Idec's proprietary non-human primate microarray. In turn, Gene Logic will grant Biogen a one-year subscription to its ToxExpress System and ToxShield services.

Biogen Idec's NHP Affymetrix GeneChip microarray includes "a comprehensive representation" of the genome of the cytomolgus monkey, as well as a "comparable cohort" of rhesus genes, Gene Logic said in a statement. The 11-micron array includes more than 51,000 probe sets.

Gene Logic said it expects the microarray will "aid in identifying drug targets and biomarkers, assessing drug toxicity, and prioritizing drug candidates."

Gene Logic will have exclusive access to the array for three years, according to the statement.

Biogen Idec will use the ToxExpress System to assess the potential toxicity of its proprietary drug candidates and will use the ToxShield Suite for "assessing and rank-ordering drug candidates based on potential toxicity in humans."

Inpharmatica Licenses Admensa Interactive to Mochida

Mochida, a Japanese pharmaceutical company, has licensed Inpharmaticals Admensa Interactive suite of predictive ADME tools, the company said last week.

Mochida is the second Japanese company to license Admensa Interactive, following Daiichi, which licensed the software in June [BioInform 06-13-05].

Mochida has taken a multi-user license to Admensa Interactive.

Financial terms of the agreement were not disclosed.

Baylor Genome Center Uses Force10 Networking System

Force10 Networks said last week that the Human Genome Sequencing Center at Baylor College of Medicine has deployed the Force10 TeraScale E-Series networking system.

HGSC is using the TeraScale E1200 to interconnect its storage facilities and research clusters and expand its network from 100 nodes to 300 and "possibly even 1,000 nodes in the future," Force10 said in a statement.

Ingenuity Sells IPA License to Schering-Plough Research Institute

Ingenuity said last week that Schering-Plough Research Institute has licensed both Ingenuity Pathways Analysis 3.0 and the Ingenuity Pathways Analysis Integration Module.

Financial terms of the agreement were not disclosed.

Drexel Receives $300K NIH Roadmap Grant for Bioinformatics Courses

Drexel University said last week that it has been awarded a two-year, $300,000 Roadmap grant from the National Institutes of Health to establish a series of courses in bioinformatics "and related subjects."

The project will be executed by Drexel University on behalf of the Greater Philadelphia Bioinformatics Alliance, a non-profit consortium of several universities and biomedical research institutes in the Philadelphia area.

Aydin Tozeren of Drexel will serve as the program's director.

Filed under

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.