Skip to main content
Premium Trial:

Request an Annual Quote

InforSense HealthSense, Pathway Studio 5.0, ImaGene 7.5, UCSC Genome Browser, GenBank 158.0, Gene Expression Omnibus, Mutation Surveyor, TMA Foresight

InforSense has launched InforSense HealthSense, a workflow-based decision support system for clinicians that is based on the InforSense KDE platform and developed in collaboration with the Windber Research Institute. Users can use HealthSense to browse and drill down into large patient data sets to identify key risk factors. The platform supports “relevant clinical data types,” the company said.

Ariadne has released Pathway Studio 5.0, which includes signaling line pathways for enhanced microarray data analysis and offers seamless integration between desktop, workgroup, and enterprise editions. The new version also gives users of the desktop edition access to the complete mammalian ResNet database.

BioDiscovery has released ImaGene 7.5, which includes extended quality controls, updated array-CGH tools, and enhanced performance for very high-density arrays of 244,000 probes or more. ImaGene now supports all GAL file formats and automatically converts a single GAL array to ImaGene’s native Meta-Grid format for enhanced grid and feature detection.

The Genome Bioinformatics Group at the University of California, Santa Cruz, has released a new session management functionality in the UCSC Genome Browser that allows users to save and share browser sessions. Users can configure their browsers with specific track combinations, including custom tracks, and save the configuraton options. Multiple sessions may be saved for future reference or for sharing with colleagues. Saved sessions last for one year after the last access, unless deleted. The new feature is accessible via the "Sessions" link in the top blue bar in any genome assembly.

The National Center for Biotechnology Information has released GenBank 158.0 here. The release contains 71,292,211,453 base pairs and 67,218,344 entries. Uncompressed, the 158.0 flat files require about 252 GB for the sequence files only. The ASN.1 version requires around 217 GB.

NCBI has also added several new features to the Gene Expression Omnibus database. GEO now includes better support for Affymetrix submissions to eliminate the need to manually transform CHP files or rename CEL files. The database also includes a new spreadsheet submission format called GEOarchive for preparing large batch submissions.

SoftGenetics has released an updated version of its Mutation Surveyor software for the automated detection of SNPs, as well as homozygous and heterozygous indels in hypervariable genome regions. This capability is expected to reduce “the tedium and errors typical in the manual review of hyper variable regions,” the company said.

Premier Biosoft has released TMA Foresight, a statistical tool for tissue microarray data analysis. TMA Foresight offers descriptive statistics such as mean, sum, and variance, as well as more advanced data correlation such as hierarchical clustering and Kaplan Meier survival plots.

Filed under

The Scan

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease, Study Finds

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer, Study Finds

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study says.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.