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InFact 2.5, Ensembl 16, eVoke, Integrated Relational Enzyme Database, BLAST

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Insightful has released InFact 2.5, an upgrade to its text analysis software targeted for the defense industry and the pharmaceutical market. According to the company, the new version offers enhanced capabilities for extracting relationships and events from natural language text. InFact 2.5 is currently available for Sun Solaris.

 

Ensembl 16 is now available at http://www.ensembl.org/. It contains new human karyotype lengths, new gene descriptions and protein features for Danio rerio, corrected LocusLink cross-references for Fugu rubripes, and other improvements.

 

Electric Genetics will launch its eVoke human gene expression ontology toolkit on August 15. The toolkit provides “untangle hierarchies” to link experimental data with consistent terms. Ontologies and mappings are updated monthly. Supported platforms include Apple OS X, Unix, and Windows.

 

The Integrated Relational Enzyme Database (IntEnz) is now available from the European Bioinformatics Institute at http://www.ebi.ac.uk/ intenz/index.html. IntEnz contains the latest version of the Enzyme Nomenclature approved by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.

 

O’Reilly and Associates has released BLAST by Ian Korf, Mark Yandell, and Joseph Bedell. The book is geared for biologists, computational biology students, and bioinformatics professionals. Further information is available at http://www.oreilly.com/ catalog/blast/.

Filed under

The Scan

Expanded Genetic Testing Uncovers Hereditary Cancer Risk in Significant Subset of Cancer Patients

In Genome Medicine, researchers found pathogenic or likely pathogenic hereditary cancer risk variants in close to 17 percent of the 17,523 patients profiled with expanded germline genetic testing.

Mitochondrial Replacement Therapy Embryos Appear Largely Normal in Single-Cell 'Omics Analyses

Embryos produced with spindle transfer-based mitochondrial replacement had delayed demethylation, but typical aneuploidy and transcriptome features in a PLOS Biology study.

Cancer Patients Report Quality of Life Benefits for Immune Checkpoint Inhibitors

Immune checkpoint inhibitor immunotherapy was linked in JAMA Network Open to enhanced quality of life compared to other treatment types in cancer patients.

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.