Skip to main content
Premium Trial:

Request an Annual Quote

iHOP, CellML API, ProteinCenter 1.1, dbGaP, MIRA 2.6

Memorial Sloan Kettering Cancer Center has released an updated version of the iHOP service, which provides summary information on more than 80,000 biological molecules by automatically extracting key sentences from millions of PubMed documents when a search is requested. The new release offers daily updates and processes about 2,000 new publications per day.

Version 1.0 of the CellML API is available here. Improvements include interface changes, performance improvements, bug fixes, and three new optional supplementary services: CellML Context, which allows user-interface programs to manage the list of models that are loaded into memory; CellML Code Generation Service, which allows C code to be generated for a model; and CellML Integration Service, which allows users to run CellML models that are systems of ordinary differential equations.

Proxeon has released ProteinCenter 1.1. The software allows users to mine proteomics data, remove redundancy, compare data sets, and get an overview of large data sets. ProteinCenter integrates sequence information and annotation from all major publicly available protein databases including GenBank, RefSeq, EMBL, UniProt, Swiss-Prot, Trembl, PIR, IPI, and Ensembl. It contains more than 7 million proteins.

The National Center for Biotechnology Information has released dbGaP (the database of Genotype and Phenotype), a new database designed to archive and distribute data from genome-wide association studies. The database provides a central location for study documentation and summaries of measured variables. It also provides pre-computed analyses of the level of statistical association between genes and selected phenotypes. The initial release contains data on two studies: the Age-Related Eye Diseases Study, a 600-subject prospective study of the clinical course of age-related macular degeneration and age-related cataracts supported by the National Eye Institute; and the National Institute of Neurological Disorders and Stroke’s Parkinsonism Study, which gathered DNA, cell line samples, and detailed phenotypic data on 2,573 subjects.

MIRA 2.6, a sequence assembly system for genome and EST sequences, is available here. The release includes new parameter switches for predefined tasks, quick switches for selecting parameters, reduced memory footprint, and increased speed.

Filed under

The Scan

Study Reveals New Details About Genetics of Major Cause of Female Infertility

Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency.

Circulating Tumor DNA Shows Potential as Biomarker in Rare Childhood Cancer

A study in the Journal of Clinical Oncology has found that circulating tumor DNA levels in rhabdomyosarcoma may serve as a biomarker for prognosis.

Study Recommends Cancer Screening for Dogs Beginning Age Seven, Depending on Breed

PetDx researchers report in PLOS One that annual cancer screening for dogs should begin by age seven.

White-Tailed Deer Harbor SARS-CoV-2 Variants No Longer Infecting Humans, Study Finds

A new study in PNAS has found that white-tailed deer could act as a reservoir of SARS-CoV-2 variants no longer found among humans.