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Idea pkExpress, MDL Decision Manager, IDRAC, Cytoscape, SeqAlert, ProSup, Genetic Association Database, ConSite


Lion Bioscience has launched Idea pkExpress, a predictive ADME (absorption, distribution, metabolism, and elimination) solution for lead optimization. The system is built upon the company’s Idea ADME prediction software and includes Lion’s new Distribution and Elimination Model, which enables users to predict the pharmacokinetic parameters of new chemical entities.

MDL Information Systems has released MDL Decision Manager, a collaborative workspace system for drug discovery researchers engaged in lead selection, validation, and optimization.

Liquent has released an updated version of IDRAC, a database of regulatory affairs information for 33 countries. The new version offers a more user-friendly interface and advanced search and navigation features, according to the company.

Version 1.1 of Cytoscape, visualization software to depict molecular interactions developed by researchers at the Whitehead Institute and the Institute for Systems Biology, is available at download/index.html.

The Weizmann Institute has released SeqAlert, a sequence-alerting service that periodically compares protein sequences of interest against sequences from determined 3D structures in the Protein Data Bank and TargetDB, at

An updated version of ProSup, a protein structure comparison server from the University of Salzburg, is available at

The Center for Information Technology at the National Institute on Aging has released the Genetic Association Database at, which allows users to compare human microarray or proteomic data against human genetic association in the context of common human disease.

ConSite, a program to detect transcription factor binding sites using phylogenetic footprinting, is available from the Center for Molecular Medicine and Therapeutics at the University of British Columbia at


Filed under

The Scan

Push Toward Approval

The Wall Street Journal reports the US Food and Drug Administration is under pressure to grant full approval to SARS-CoV-2 vaccines.

Deer Exposure

About 40 percent of deer in a handful of US states carry antibodies to SARS-CoV-2, according to Nature News.

Millions But Not Enough

NPR reports the US is set to send 110 million SARS-CoV-2 vaccine doses abroad, but that billions are needed.

PNAS Papers on CRISPR-Edited Cancer Models, Multiple Sclerosis Neuroinflammation, Parasitic Wasps

In PNAS this week: gene-editing approach for developing cancer models, role of extracellular proteins in multiple sclerosis, and more.