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IBM Clinical Genomics Solution, DivCon Discovery Suite 2.1.5, UCSC Genome Browser, Blat, Ensembl, NCBI Web Service, ElNmo, EMBOSS 2.9.0


IBM has released the IBM Healthcare and Life Sciences Clinical Genomics Solution, a set of tools and services for integrating, storing, and analyzing genotypic and phenotypic data. Components include a Medical Information Broker, a Medical Information Repository, and the DB2 Information Integrator.

QuantumBio has released DivCon Discovery Suite 2.1.5 for Linux and Mac OS X. The package includes five modules for computer-assisted molecular modeling.

The University of California Santa Cruz genome bioinformatics group has released the latest mouse assembly (NCBI build 33) via the UCSC Genome Browser and Blat server. Ensembl has also provided the assembly via its pre-release site,, and plans to release a fully annotated assembly in September.

A new version of the NCBI Web Service enables developers to access Entrez Utilities via SOAP. Further details are at

ElNémo, a web server for predicting the movements of macromolecules, is available from the Centre National de la Recherche Scientifique at

EMBOSS 2.9.0 is available at New features include modifications support development of an EMBOSS ontology. In addition, EMBASSY packages can now be compiled and linked against an installed version of EMBOSS.

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The Scan

Suicidal Ideation-Linked Loci Identified Using Million Veteran Program Data

Researchers in PLOS Genetics identify risk variants within and across ancestry groups with a genome-wide association study involving veterans with or without a history of suicidal ideation.

Algorithm Teases Out Genetic Ancestry in Individuals at Biobank Scale

Researchers develop an algorithm known as Rye to tease apart ancestry fractions in admixed individuals at a biobank-scale, applying it to 488,221 UK Biobank participants in Nucleic Acids Research.

Multi-Ancestry Analysis Highlights Comparable Common Variants at Complex Trait-Linked Loci

Researchers in Nature Genetics examine common variants implicated in more than three dozen conditions, estimating genetic effect similarities across ancestry tracts in admixed individuals.

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.