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Human Genome Will Be Defined by Spring 2000, HGP Scientists Confirm

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HINXTON, UK--With one quarter of the human genome in the public domain, scientists have confirmed that they are on schedule to produce the first draft of the entire genome by spring 2000, according to the Human Genome Project scientists who gathered for the Fifth International Strategy Meeting on Human Genome Sequencing here at the Wellcome Trust Genome Campus. The project's international consortium stated that it jointly has enough sequencing capacity to provide a working draft of 90 percent of the euchromatic or gene rich part of the human genome by spring 2000. To date, 739 million base pairs, or roughly one quarter of the human genome, have been deposited in GenBank in finished or near finished form. The sequences of several individual chromosomes are nearing completion, and the first of these likely will be announced before the end of the year.

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The Scan

For Better Odds

Bloomberg reports that a child has been born following polygenic risk score screening as an embryo.

Booster Decision Expected

The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.