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Horizon Discovery, Desktop Genetics to Develop CRISPR Design Platform

NEW YORK (GenomeWeb News) – Horizon Discovery today said that it is collaborating with Desktop Genetics to develop a CRISPR design platform.

The Cambridge, UK-based firm said that Desktop Genetics will design and implement algorithms based on input from Horizon, which said it will use the platform to quickly identify the best guide-RNAs in the human genome for each gene editing task as part of its Genesis portfolio of gene editing technologies.

CRISPR is an RNA-guided gene editing system that can introduce either a targeted double strand break or single strand nick in the genome of mammalian cells. Earlier this year Horizon non-exclusively licensed the CRISPR gene editing technology from Harvard University.

Terms of the alliance with Desktop Genetics were not disclosed.

London-based Desktop Genetics develops software tools for a variety of molecular biology research applications including gene expression, cell line development, and gene editing.

The Scan

Gone, But Now Reconstructed SARS-CoV-2 Genomes

In a preprint, a researcher describes his recovery of viral sequences that had been removed from a common database.

Rare Heart Inflammation Warning

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Sandwich Sampling

The New York Times sent tuna sandwiches for PCR analysis.

Nature Papers Describe Gut Viruses, New Format for Storing Quantitative Genomic Data, More

In Nature this week: catalog of DNA viruses of the human gut microbiome, new dense depth data dump format to store quantitative genomic data, and more.