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Horizon Discovery, Desktop Genetics to Develop CRISPR Design Platform

NEW YORK (GenomeWeb News) – Horizon Discovery today said that it is collaborating with Desktop Genetics to develop a CRISPR design platform.

The Cambridge, UK-based firm said that Desktop Genetics will design and implement algorithms based on input from Horizon, which said it will use the platform to quickly identify the best guide-RNAs in the human genome for each gene editing task as part of its Genesis portfolio of gene editing technologies.

CRISPR is an RNA-guided gene editing system that can introduce either a targeted double strand break or single strand nick in the genome of mammalian cells. Earlier this year Horizon non-exclusively licensed the CRISPR gene editing technology from Harvard University.

Terms of the alliance with Desktop Genetics were not disclosed.

London-based Desktop Genetics develops software tools for a variety of molecular biology research applications including gene expression, cell line development, and gene editing.

The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.