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HapMap Release 21, UCSC Genome Browser, siVirus

The International HapMap Project has made genotypes, frequencies, and assays for phase I and phase II of the HapMap project available for bulk download at HapMap Release 21 contains all processed data from the HapMap project, as well as genotypes from the Affymetrix 500K genotyping array.

The Genome Bioinformatics Group at the University of California Santa Cruz has released a Genome Browser for the Build 2, version 1, assembly of the chimpanzee (Pan troglodytes) genome. The 6X whole-genome assembly contains sequence from the initial 4X assembly published in Nature last year, with additional 2X sequence from the Genome Sequencing Center of Washington University School of Medicine. The assembly covers about 97 percent of the genome and is composed of 265,882 contigs. Bulk downloads of the sequence and annotation data are available via FTP ( or the UCSC downloads page (

The University of Tokyo has launched siVirus, a web-based antiviral siRNA design tool that searches for functional, off-target minimized siRNAs targeting highly conserved regions of divergent viral sequences, according to the researchers. The software, which currently covers HIV-1, hepatitis C, SARS, and influenza, is available at

Filed under

The Scan

Just Breathing

A new analysis suggests that most Mycobacterium tuberculosis is spread by aerosols from breathing, rather than by coughing, the New York Times reports.

Just Like This One

NPR reports that the World Health Organization has hired a South African biotech company to recreate mRNA vaccine for SARS-CoV-2 that is similar to the one developed by Moderna.

Slow Start

The Wall Street Journal reports that Biogen's Alzheimer's disease treatment had revenues for July through September that totaled $300,000.

Genome Research Papers on Cancer Chromatin, Splicing in the Thymus, Circular RNAs in Cancer

In Genome Research this week: analysis of bivalent chromatin sites, RBFOX splicing factors' role in thymic epithelial cells, and more.