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GenomeQuestLive, Pfam 14.0, S+ArrayAnalyzer 2.0, Entrez programming utilities, HapMap data release 8, RESID


Gene-IT has launched GenomeQuestLive, an online version of the company’s GenomeQuest sequence search software. According to Gene-IT, half a dozen biotech companies have already signed up for the new service, including Serono and Axxam. GenomeQuestLive offers secure web-based IP and functional sequence searching and analysis for patent agents, attorneys, research directors, and scientists, the company said. Gene-IT is offering the service in a “pay as you go” model.

Pfam 14.0 is available from the Pfam consortium at and mirror sites. Version 14.0 contains 7,459 protein families.

Insightful has released S+ArrayAnalyzer 2.0, a new version of its microarray analysis software based on the S-Plus data analysis platform. S+ArrayAnalyzer provides statistical software workflows for data access, QC data diagnostics, data preparation, statistical modeling, and annotated graphical reporting, the company said. New features include enhanced access and analysis for Affymetrix and two-channel microarray data; interfaces for both desktop and Web; and increased accuracy for low-replicate experiments. The software requires S-Plus 6.2 and MS Windows XP Pro, 2000, or 2003 Server.

The National Center for Biotechnology Information has released a SOAP interface for the “eutils” Entrez programming utilities at

Accelrys has released the AE (Accord Enterprise) Webkit, a tool that allows users to build and customize their own cheminformatics applications using validated components and web browser-based user interfaces. This is the first in a series of planned Webkit releases, the company said.

The HapMap Data Coordination Center at Cold Spring Harbor Laboratory has posted HapMap data release 8 at The release contains 614,030 genotype sets from the 90 CEPH-panel samples, totaling 55,262,700 genotypes.

The European Bioinformatics Institute has released version 37.02 of the RESID database of protein modifications, a collection of annotations and structures for protein modifications including amino-terminal, carboxyl-terminal, and peptide chain cross-link post-translational modifications. The database is available at The release contains 363 entries: 244 entries are annotated in both PIR and Swiss-Prot; 34 entries are annotated in PIR and not Swiss-Prot; 43 entries are annotated in Swiss-Prot and not PIR; and 34 entries are not annotated in either PIR or Swiss-Prot.

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The Scan

Booster for At-Risk

The New York Times reports that the US Food and Drug Administration has authorized a third dose of the Pfizer-BioNTech SARS-CoV-2 vaccine for people over 65 or at increased risk.

Preprints OK to Mention Again

Nature News reports the Australian Research Council has changed its new policy and now allows preprints to be cited in grant applications.

Hundreds of Millions More to Share

The US plans to purchase and donate 500 million additional SARS-CoV-2 vaccine doses, according to the Washington Post.

Nature Papers Examine Molecular Program Differences Influencing Neural Cells, Population History of Polynesia

In Nature this week: changes in molecular program during embryonic development leads to different neural cell types, and more.